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December 22, 1956

Thiopentone and Other Thiobarbiturates

JAMA. 1956;162(17):1580. doi:10.1001/jama.1956.02970340070030

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This book should rapidly come to be considered one of the classics in the literature of anesthesia. The author has condensed into a relatively few pages the pertinent mass of literature that has accumulated on this vital subject. This book is logically and clearly prepared in a fashion that makes it easy and pleasant to read, yet it is definitely informative. Although the author does not hesitate to express his opinion, he gives due consideration to the controversial aspects of the subject and, in the final analysis, presents the reader with the known as well as the unknown of the subject of anesthesia. This book is organized into 12 chapters dealing with history; physical properties and chemistry; distribution and fate in the body; the effects of thiobarbiturates on the body; variations in response to thiobarbiturates; the use of thiopental sodium in certain pathological conditions; hazards, therapeutic uses, and administration of

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