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November 15, 1952


Author Affiliations

From the Cleveland Clinic and the Frank E. Bunts Educational Institute.

JAMA. 1952;150(11):1069-1073. doi:10.1001/jama.1952.03680110009003

The prognosis of the immediate illness in acute myocardial infarction is determined principally by the size of the infarcted area and by whether certain complications develop. In patients who recover, ultimate longevity and the degree of functional rehabilitation attained depend to a large extent on whether certain sequelae occur. The purpose of this paper is to review the most important of the complications and sequelae of acute myocardial infarction, with particular reference to their clinical features and to the prevention or treatment of those for which prophylactic or therapeutic measures are available.

COMPLICATIONS  The principal complications of acute myocardial infarction are shock, acute left ventricular failure, congestive heart failure, abnormalities of cardiac rhythm, thromboembolism, rupture of the ventricle, perforation of the interventricular septum, and rupture of a papillary muscle. Each of these conditions will be considered briefly.

Shock.  —A shock-like state of mild to severe degree occurs in 50% or