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Disease of the Diencephalon and Psoriasis.
—The pathogenesis of psoriasis has long been the subject of research in France. Margarot, Bolgert, Poisson, and Soulié considered it a psychodermatosis, while Professor Charpy of the Marseilles school thought it to be an adaptation syndrome. Even many patients believed the origin of their disease to be emotional, but this remained to be proved. Fabre, Pitot, and Mrs. Pitot-Muzard have attempted to clear up this obscure pathogenesis without any tangible evidence. The authors thought that these causes, to be taken into account, must have acted in predisposed environments due to perturbation of receptive centers. The existence of a stress is conditioned by two factors: the aggression and the organism reacting to it, without which there is no syndrome. According to Camus and Roussy's works and those of Margarot, the authors have been looking for the reception of the aggression into the diencephalon and hypothalamus
PARIS. JAMA. 1952;150(12):1240. doi:10.1001/jama.1952.03680120076023
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