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June 2, 1956


JAMA. 1956;161(5):448. doi:10.1001/jama.1956.62970050015010a

This case presents an infrequently recognized sequence of events: carcinomatous embolization of the lungs from breast cancer metastatic in the liver. A similar case was described by Mason in 1940.1 There is, however, an interesting difference between his patient and the one here presented. His patient, like those of Greenspan2 and Brill and Robertson,3 who also had metastatic cancer to the smaller pulmonary vessels, died of failure of the right side of the heart. This patient had no clinical evidence of failure of the right side of the heart, but died of anoxia. Fulton4 describes these two types of death and states that the anoxic death occurs in the more rapidly progressive disease. This patient had symptoms of three weeks' duration. The anatomic evidence is compatible with the occurrence of several showers of tumor emboli. The earlier showers produced dyspnea and cyanosis and the final shower,

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