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June 2, 1956

Neural Control of the Pituitary Gland

JAMA. 1956;161(5):484. doi:10.1001/jama.1956.02970050086028

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It is now evident that the pituitary gland does not enjoy the autonomous control implicit in such expressions as "the master gland" or "the leader of the endocrine symphony" by which it was formerly designated. A reciprocal relationship exists between the pituitary, as well as other endocrine glands, and the nervous system. The latter not only regulates these glands but is in turn affected by their activity. The hypothalamus in particular, through its intimate vascular connection with the pituitary, is vitally concerned in regulating hypophysial activity. Professor Harris, who has contributed much to this field, has summarized the available data in a clear and masterful manner. Presenting both sides of what in many aspects is still a controversial subject, he has objectively and critically analyzed the current experimental and theoretical aspects of the subject. He surveys the nerve and blood supply and neurovascular control of the pituitary, the transplantation of

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