The patient whose case is to be reported had manifestations of the nephrotic syndrome as a result of infection with Plasmodium malariae. The evidence indicated that the child acquired malaria congenitally from the mother, a narcotic addict, who had acquired her infection by syringe inoculation. The patient's clinical course, the changes in concentration of the plasma proteins and lipids, and the quantitative urinary output of protein and formed elements were studied during therapy with chloroquine phosphate. A complete remission of the nephrotic syndrome occurred.
Report of a Case
The patient, a 21-month-old Negro female, was admitted to the Clinical Center of the National Institutes of Health with a history of facial and abdominal swelling of three months' duration. She was delivered out of wedlock in the prison section of District of Columbia General Hospital, Washington, D. C. The delivery was normal and the neonatal course uneventful. The baby was nursed
Keitel HG, Goodman HC, Havel RJ, Gordon RS, Baxter JH. NEPHROTIC SYNDROME IN CONGENITAL QUARTAN MALARIA. JAMA. 1956;161(6):520–523. doi:10.1001/jama.1956.62970060001009
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