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December 27, 1952


JAMA. 1952;150(17):1716. doi:10.1001/jama.1952.03680170070016

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Thromboangiitis Obliterans.  —In the Istanbul periodical Pratik Doktor, Dr. Feridun Timur, chief of Tekirdag General Hospital's medical department, reported a severe case of thromboangiitis obliterans. The patient, a sturdy farmer aged 46, who before the onset of the disease had always been in good health, has undergone 18 amputations in 16 years. He has lost both legs, the right arm, and three fingers of the left hand. At first, he had felt a pain in the right leg while walking, and cyanosis had followed. From time to time the pain diminished, but it forced him to limp. Six months later there was cyanosis of the big toe and of the toe next to it, and a small wound developed that healed when treated. A year later the toes became gangrenous and had to be amputated. For eight months afterward the patient remained in the hospital under treatment, but there was

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