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March 2, 1957

Physiology of the Ocular and Cerebrospinal Fluids

JAMA. 1957;163(9):793. doi:10.1001/jama.1957.02970440089030

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This book was written by a physiologist who has worked on the aqueous humor for more than 20 years and on cerebrospinal fluid for 4 years. The first two chapters present an authoritative and competent review of the morphology of those structures that are important to an understanding of the physiology and pathophysiology of the two fluids. Chapters 3 through 8 deal with the composition of the fluids; their formation, circulation, and absorption; the blood-aqueous, blood-vitreous. blood-cerebrospinal fluid, and blood-brain barriers; significant isotope studies; and changes in the physiology of the fluids resulting from disease and other causes, such as age. The last chapter contains a discussion of fluid-pressure relationships, including alterations due to drugs and disease. Each chapter is followed by a comprehensive and yet selective reference list, which emphasizes the thoroughness and competence with which the author has reviewed the pertinent literature. His criticisms are frank, fair, and

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