Radiologic examination of the urinary tract in infants is frequently a trying experience because of the technical aspects of venipuncture. Urography may be accomplished by the intramuscular injection of a 15% to a 35% solution of iodopyracet (Diodrast) compound,1 but in my experience this has been painful to the infant. The addition of hyaluronidase for the subcutaneous or the intramuscular administration of iodopyracet has been recommended by Olsson and Löfgren2 and Astley,3 while Fainsinger4 and Begley5 prefer the intramuscular use of the contrast medium after the site of injection has previously been prepared by the administration of hyaluronidase.
Subcutaneous urography was used by Nesbit and Douglas6 in 31 patients of various ages. They used 20 cc. of a 35% solution of iodopyracet diluted to 100 cc. with isotonic sodium chloride solution; half of the mixture was injected over the angle of each scapula. Others
Epstein BS. SUBCUTANEOUS UROGRAPHY IN INFANTS. JAMA. 1957;164(1):39–41. doi:10.1001/jama.1957.62980010001009
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