[Skip to Content]
[Skip to Content Landing]
March 30, 1957


JAMA. 1957;163(13):1135-1137. doi:10.1001/jama.1957.82970480001008

Hyperlipemia is a condition in which there is an increase of the neutral fat in the serum. If this increase is of sufficient degree, the serum may become milky in appearance. The disproportionate increase in neutral fats, rather than the absolute increase in the total lipid concentration, is responsible for the milkiness of the serum. This lactescence is due to the large size of the fat particles; an increase of cholesterol or phospholipids without an increase of neutral fat never causes milky serum. Thannhauser1 states that the designation hyperlipemia should be reserved exclusively for an abnormal increase of neutral fat in the serum, whereas the terms "hyperlecithinemia" and "hypercholesteremia" should be used to designate the increase of these lipids in the serum. Hyperlipemia is observed under a number of pathological conditions, such as lipid nephrosis, the nephrotic state of glomerulonephritis, thrombosis of the renal veins, diabetes mellitus, pancreatitis, hepatic