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May 11, 1957


Author Affiliations

Department of Dermatology Temple University Medical Center Philadelphia 40.

JAMA. 1957;164(2):205. doi:10.1001/jama.1957.02980020085024

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To the Editor:—  Smallpox vaccination has long been used with sporadic success in the treatment of recurrent cases of herpes simplex. The following observations on two patients who came in contact with poliomyelitis viruses may be of some value in the future treatment of recurrent herpes simplex.A 25-year-old man gave a history of repeated attacks of herpes simplex on the lower lip since childhood. These episodes would occur about every three months, but the patient had never previously seen a physician for any form of treatment. During the first seven months of 1956, he was employed in the department of virology of Temple University Medical Center as a laboratory technician. During the course of his occupation, he would use pipets in transferring tissue cultures containing the HeLa cell which was impregnated with all three types of poliomyelitis virus. On many occasions this transfer would result in the accidental ingestion

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