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May 11, 1957


Author Affiliations

945 Fifth Ave. New York 21.

JAMA. 1957;164(2):205. doi:10.1001/jama.1957.02980020085025

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To the Editor:—  The article "Combination Therapy of Retinoblastoma with Triethylene Melamine and Radiotherapy," by George A. Hyman and Algernon B. Reese, in The Journal, Dec. 8, 1956, page 1368, is a significant contribution to the literature on this rare tumor. Few institutions could assemble 50 children with retinoblastoma for report to the medical world. The work reported once again showed an important relationship between chemotherapy and radiotherapy.Those of us who see only rarely a patient with retinoblastoma will refer to the results in this large series of patients. In using the article as a reference, there are striking limitations to the description of the radiation therapy. To describe radiotherapy dosage as "5,600 to 8,000 r in air to the tumor" or "2,400 r in air to the tumor" is both inaccurate and insufficient for those readers who would like to duplicate the technique. Of invaluable aid to the

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