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Article
June 30, 1956

ANOMALOUS TYPE OF SALT AND WATER RETENTION WITH PERSISTENT EDEMA: REPORT OF A CASE

JAMA. 1956;161(9):877-879. doi:10.1001/jama.1956.62970090018017j
Abstract

The effect of the central nervous system upon salt and water metabolism is being noted more frequently, particularly as a postoperative neurosurgical complication. Over the past three years (since October, 1952) we have had the opportunity of studying a case of apparent postencephalitic involvement of the central nervous system affecting salt and water metabolism, presumably through the neurohypophysis. It is the purpose of this report to reviewthe pertinent features of the clinical and laboratory records of this patient and the record of the diuretic response to various agents and to suggest the possible mechanism of the salt and water retention.

A 35-year-old woman was in excellent health until 1946, when she developed nausea, clumsiness of motion, drowsiness, and difficulty in focusing her vision. She was in her second month of a pregnancy. A diagnosis of encephalitis was made by the consulting neurologist, and a therapeutic abortion was performed. She recovered

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