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In this volume the author stresses the importance of the uniqueness of the individual as opposed to the similarity between individuals. If one considers the wide variations existing in many clinical values in the so-called normal person, it becomes readily apparent that, when extremes are persistent in normal persons, these individuals differ profoundly even though clinical values are within the normal. Such differences are not surprising when one considers the numerous enzymatic reactions controlling body functions and the results when several of these reactions are functioning other than optimally.
The first two chapters may be considered introductory, in that the author establishes the significance of biochemical variation and the basis for biochemical individuality. The next eight chapters point out areas of existing individuality in anatomy, chemical composition of the body, enzyme patterns, endocrine activity, excretion patterns, drug response, and nutrition. The latter area includes a discussion on the amounts of
Biochemical Individuality: The Basis for the Genetotrophic Concept. JAMA. 1957;164(3):351. doi:10.1001/jama.1957.02980030127035
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