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May 25, 1957


Author Affiliations

Chief, Division of Pharmacology, Food and Drug Administration, Department of Health, Education, and Welfare, Washington, D. C.

JAMA. 1957;164(4):416. doi:10.1001/jama.1957.02980040056014

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During the past several decades, the popularity of cosmetic preparations has increased so considerably that, at present, their general use has become almost a necessity for the average woman. As such, these preparations are leaving the realm of luxury items. This demand has led to the new use of many known substances and the development and extensive manufacture of new synthetic compounds for incorporation into such products. Unfortunately, carefully controlled research by competent investigators, particularly concerning the fundamental principles of skin properties and mechanisms and the related problems in skin pharmacology and toxicology, has not kept pace with the many new products and the claims made in their behalf.

Certain unobjectionable claims have been advanced for the efficacy of certain cosmetic preparations for mitigating skin dryness, hiding skin blemishes and wrinkles, and affording a continued healthy and youthful appearance to the skin. In recent years, however, the trend has been

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