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The first edition of this important work appeared in 1933, and the present edition represents an effort to assimilate the immense number of contributions that have been made in the field of serology since that time, in both Europe and America. Issued in 18 installments, the book is now complete and totals 1,117 pages. The six major divisions deal with antigens, antibodies, the antigen-antibody complex, the formation of antibodies, indirect and secondary effects of the antigen-antibody reaction, and special serologic reactions. The first division may be taken as an example of the comprehensiveness of the work. It contains sections on specificity and the haptene concept, proteins in general, the specificity of proteins, chemically altered proteins, artificially conjugated antigens, carbohydrate-protein combinations, serologic experiments with chemically marked antigens, reactions of simple compounds of known composition, the limits of specificity, microbial antigens, bacterial toxins and animal poisons, heterogenetic antigens and antibodies, viruses, and
Fortschritte der Serologie. JAMA. 1957;164(5):616. doi:10.1001/jama.1957.02980050106029
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