[Skip to Content]
[Skip to Content Landing]
Article
June 8, 1957

SIMPLIFIED TEST OF FAT ABSORPTION: COMPARISON OF SERUM TURBIDITY, CHYLOMICRONEMIA, AND TOTAL LIPID VALUES AFTER FAT TEST MEAL

JAMA. 1957;164(6):633-638. doi:10.1001/jama.1957.02980060009003
Abstract

• The lipemia following ingestion of fat was studied in 15 healthy subjects and 4 patients with pancreatic insufficiency. In addition to serum turbidity measurements and chylomicron counts, chemical methods were used to obtain values for total lipid, neutral fat, cholesterol, and phospholipid. In healthy subjects the ingestion of 1 Gm. of fat per kilogram of body weight gave satisfactory rises in serum turbidity, total lipid, and neutral fat, while 0.5 Gm. per kilogram sufficed to give rises in turbidity and chylomicron counts. The 0.5 Gm. per kilogram dose given to the patients with pancreatic insufficiency was not followed by consistent or significant rises in turbidity, chylomicron count, or total lipid. Serial determinations of serum turbidity after administration of fat therefore appeared to offer a simple method of following fat absorption and utilization and to constitute a clinical test applicable to various gastrointestinal and metabolic diseases.

×