• The results of surgery and radiation have been studied in 1,066 patients treated for carcinoma of the larynx from 1930 to 1955. The treatment was partial laryngectomy in 384 cases, total laryngectomy in 374, laryngectomy with radical dissection of the neck in 48, and irradiation in 260. Data on five-year survival were obtained in 695 patients; the rate was highest (87%) for partial laryngectomy, intermediate (64%) for total laryngectomy, and lowest (42%) for irradiation. There were 201 patients in whom total laryngectomy was the initial treatment, who did not die of other causes, and who were followed up after operation; 37 of these developed cervical metastases. Of the 14 in this group who were treated by irradiation alone, none survived. Comparison of the most recent figures with those reported in 1948 showed that the over-all survival rate had remained unchanged at 72%.
Jackson CL, Blady JV, Norris CM, Robbins R. CARCINOMA OF THE LARYNX: SURVEY OF 25 YEARS' EXPERIENCE IN TREATMENT BY SURGERY AND IRRADIATION. JAMA. 1957;163(17):1567–1570. doi:10.1001/jama.1957.02970520001001
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