It has been emphasized1 that there are millions of children in the world today infected with primary tuberculosis who will constitute a significant proportion of adults suffering from tuberculosis tomorrow. Even if clinically manifest disease does not develop during childhood, a number of these infected children will be afflicted with active tuberculosis when they grow up and will in turn infect their children.Until recently, few physicians were interested in the treatment of children with primary tuberculosis, as most children recovered spontaneously without clinical evidence of the disease. Some developed complications such as meningitis and miliary tuberculosis and died, since no specific therapy was available.2Better methods of diagnosis and treatment have encouraged a new approach in the control of tuberculosis among the young.3 Today the tuberculin test has become increasingly important in the United States in the detection of the disease because of the decrease
RESEARCH REVIEWS. JAMA. 1957;164(6):715–718. doi:10.1001/jama.1957.02980060091028
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