[Skip to Content]
[Skip to Content Landing]
Article
June 15, 1957

ALDOSTERONE-PRODUCING TUMORS OF THE ADRENAL GLAND: REPORT OF THREE CASES

JAMA. 1957;164(7):719-726. doi:10.1001/jama.1957.02980070001001
Abstract

• A total of 16 cases of primary aldosteronism have been reported in the literature. Twelve of the patients have been cured: 10 by the removal of an adrenocortical adenoma, one by total adrenalectomy, and one by subtotal adrenalectomy. In three cases, reported in detail, the sodium-retaining substance was identified as aldosterone diacetate and was present in large amounts in the urine. There appears to be a distinct entity, with typical clinical, biochemical, and renal findings, that should lead the physician to suspect the presence of primary aldosteronism.

×