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Article
April 27, 1957

Liver: Structure and Function

JAMA. 1957;163(17):1658. doi:10.1001/jama.1957.02970520092030

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Abstract

In this volume the subject of liver disease is presented from the point of view of the pathological anatomist and the pathological physiologist. Within the bounds of present knowledge, structural changes in the liver are correlated with biochemical and other functional changes as well as with clinical findings. The first section deals in detail with normal structure and function of the liver. In part 2, general pathological phenomena are discussed, including jaundice, inflammation, cholestasis, fatty metamorphosis, fibrosis, and cirrhosis. Part 3 is devoted to liver function tests, including the use of x-ray and liver biopsy. Specific diseases of the liver are described in parts 4 and 5 and tumors in part 6. In the final section is a discussion of the relation of the liver to the hematopoietic system, to the gastrointestinal tract, to the endocrine glands, and to other systems in the body and of the hepatic response to

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