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June 15, 1957


Author Affiliations

536 Front St. Hempstead, N. Y.

JAMA. 1957;164(7):797-798. doi:10.1001/jama.1957.02980070079021

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To the Editor:—  The authors of the letter are completely justified in their constructive criticism of hypometabolism or metabolic insufficiency. However, my paper was only a preliminary report and primarily one concerning the use of the thyroid hormone in infants and children. Follow-up studies, which appeared in the form of an exhibit at the American Academy of Pediatrics meeting in October, 1956, gave more complete and detailed information. The average dose of thyroxinThis letter was referred to the author of the article, who replied in part as follows: was 0.4 mg. daily and thyroglobulin was 3 grains daily. The maximum dose for each patient was determined by his individual tolerance, so that the clinical response and results reported, even though not purely objective ( and I have made allowances for the objectivity of the parents ) were only partially interpreted. The more important clinical changes which denoted improvement were the objective

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