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Article
July 13, 1957

DIAGNOSIS AND ANTIMICROBIAL THERAPY OF PRIMARY TUBERCULOSIS IN CHILDREN

JAMA. 1957;164(11):1204-1209. doi:10.1001/jama.1957.02980110030006
Abstract

• Awareness of the possibility of tuberculosis, especially of primary tuberculosis in children, is more important for the diagnosis of this condition than anything else. Tuberculin testing, using purified protein derivative, is the most effective method of detecting primary tuberculosis, since most of the children harboring this disease appear perfectly well and the majority have normal-appearing chest roentgenograms. Isoniazed, given in conjunction with aminosalicylic acid, is the most potent and least toxic antituberculosis drug known; and, while it does not assure eradication of the infection, an adequate course of therapy greatly minimizes the chance of serious tuberculous diseases.

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