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Article
July 13, 1957

Brain Mechanisms and Drug Action: A Symposium, Fourth Annual Scientific Meeting of the Houston Neurological Society, Texas Medical Center, Houston, Texas

JAMA. 1957;164(11):1288. doi:10.1001/jama.1957.02980110114024

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Abstract

This timely volume illustrates what a progressive and alert neurological society can accomplish. The Houston (Texas) Neurological Society has not only had a fourth annual scientific meeting but it has also summarized the papers and discussions presented in this book. The scientific meeting was made possible by the collaboration of eight visiting scientists and two scientists from Baylor University College of Medicine. The symposium dealt with the possible modes of action of transquilizing drugs. Under the general headings of (1) reticular formation, (2) central synapses, (3) afferent pathways, (4) hypothalamus-pituitary-adrenal axis, and (5) animal behavior, neuropharmacological data were discussed. The neuropharmocological effects of chlorpromazine hydrochloride, reserpine, barbiturates, lysergic acid diethylamide (LSD-25), amphetamine, and 5-hydroxytryptamine are reviewed in relationship to the above categories. The individual papers are well written and informative. The discussions are inadequately edited so that the discussants' points of view are frequently hard to interpret. The volume makes

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