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July 20, 1957

Tranquilizing Drugs: A Symposium Held under the Auspices of the American Association for the Advancement of Science in Cooperation with the American Psychiatric Association and the American Physiological Society and Presented at the Atlanta, Georgia, Meeting, December 27-28, 1955

JAMA. 1957;164(12):1412. doi:10.1001/jama.1957.02980120116024

This small volume includes 14 papers. An introductory note by Dr. Chauncey D. Leake contains a classification scheme for the various types of drugs used in mental disorders and outlines some of the problems confronting investigators in this field. The first part of the book is devoted to several basic papers on the electrophysiological and metabolic aspects of tranquilizing drug action. There is one paper on the action of benztropine methanesulfonate in paralysis agitans. These presentations shed some light on the possible mechanisms and sites of action of the more commonly used agents. In addition to providing information on drug-induced alterations in neural function, the techniques discussed should be of value to other investigators as a possible means of screening and evaluating newly developed tranquilizing agents. Of particular interest is the paper on adrenolutin, an epinephrine derivative that elicits a number of abnormal psychological and psychic responses. In view of

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