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August 3, 1957

Diabetes Mellitus With Emphasis on Children and Young Adults

JAMA. 1957;164(14):1625. doi:10.1001/jama.1957.02980140101024

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This is a unique book on diabetes mellitus. In contrast to the usual approach to the subject, the emphasis is on the biochemical and hormonal aspects of the disease. In the first of three sections the author gives a thorough, modern review of experimental diabetes and the interaction of the endocrine glands in glucose metabolism. References are complete and the brief summaries at the end of each chapter are valuable. The second section is a collection of more practical data. Drawing heavily on his own observations, the author considers the magnitude of the diabetic problem, particularly the juvenile form. He includes valuable sections on interpretation of the glucose tolerance curve, renal glycosuria, and the electrolyte changes accompanying insulin and glucose administration. Glucagon and epinephrine are briefly discussed. Therapy of diabetes is considered, with emphasis on the metabolic effects of insulin administration. The highlight of the final section, which is otherwise

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