• Experience with the cyclopropane-curare type of general anesthesia in 1,011 cesarean sections has been analyzed and compared with published reports on the use of other types of anesthesia for this operation. All patients in this series received scopolamine with or without additional premedication, and after the induction of anesthesia with cyclopropane an injection of 6 to 12 mg. of tubocurarine chloride was given intravenously. The one maternal death in this series occurred two weeks after the operation and was not related to the anesthesia. The associated gross infant mortality rate was 5.4%, of which 2.9% were stillbirths and 2.5% were neonatal deaths, but when this figure was corrected for prematurity, congenital anomalies, and other factors clearly unrelated to the anesthesia, the net rate was 4.7%, with 2.4% for stillbirths and 2.3% for neonatal deaths. These findings conflict with claims that have been made for the superiority of other methods of anesthesia. The good results here reported are ascribed in part to the care and observation given to the individual patient before the operation as well as to the attention given in the recovery room. It is therefore recommended that trained anesthesiologists be kept available for obstetric patients throughout the 24-hour day.
Allen HL, Weekley AS, Metcalf DW. PERFORMANCE OF CESAREAN SECTION WITH AID OF GENERAL ANESTHESIAANALYSIS OF ONE THOUSAND ELEVEN OPERATIONS SINCE 1948. JAMA. 1957;164(16):1743–1746. doi:10.1001/jama.1957.02980160015004
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