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August 24, 1957

The Metabolic Response to Neonatal Surgery

JAMA. 1957;164(17):1991. doi:10.1001/jama.1957.02980170131024

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This volume presents a detailed biochemical and physiological study of the metabolic changes that occurred in nine patients who were operated on during the neonatal period. It summarizes over 3,500 chemical determinations made before and immediately after operation. The postoperative period is studied until the patient has achieved some stability. Emphasis is on quantitative measurement of the patient's intake (nutrition, fluids, electrolytes, and blood) and output (secretions, urine, stools, and perspiration). In spite of the small number of patients analyzed, the book represents a prodigious amount of work and is an excellent beginning toward providing information concerning metabolic changes associated with neonatal operations. It is, in fact, a very good reference book for those interested in the problem. An introductory summary of the available data on metabolic changes during operations in adults is provided, and these data are compared with information available about neonatal operative changes. The analytical methods used

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