Patients with achlorhydria and hypochlorhydria show a much greater disposition to gastric cancer. Further, the early detection of pernicious anemia presents a problem because of the plethora of proprietary hematinics. As an aid to cancer detection, the tubeless method of determining free hydrochloric acid in the stomach removes many of the previous inconveniences which have discouraged widespread use of this screening test. However, pyloric obstruction, impairment of small intestinal absorption, hepatic disease, and impairment of renal function may interfere with the accuracy of the test.
Fentress V, Sandweiss DJ. SEGAL'S TUBELESS GASTRIC ANALYSIS WITH AZURE A RESIN COMPOUNDA SIMPLE PROCEDURE FOR SCREENING INDIVIDUALS WITH ACHLORHYDRIA IN A GASTRIC CANCER DETECTION PROGRAM. JAMA. 1957;165(1):21–24. doi:10.1001/jama.1957.02980190023005
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: