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Article
September 7, 1957

SEGAL'S TUBELESS GASTRIC ANALYSIS WITH AZURE A RESIN COMPOUNDA SIMPLE PROCEDURE FOR SCREENING INDIVIDUALS WITH ACHLORHYDRIA IN A GASTRIC CANCER DETECTION PROGRAM

JAMA. 1957;165(1):21-24. doi:10.1001/jama.1957.02980190023005
Abstract

Patients with achlorhydria and hypochlorhydria show a much greater disposition to gastric cancer. Further, the early detection of pernicious anemia presents a problem because of the plethora of proprietary hematinics. As an aid to cancer detection, the tubeless method of determining free hydrochloric acid in the stomach removes many of the previous inconveniences which have discouraged widespread use of this screening test. However, pyloric obstruction, impairment of small intestinal absorption, hepatic disease, and impairment of renal function may interfere with the accuracy of the test.

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