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September 7, 1957

Morphine & Allied Drugs

JAMA. 1957;165(1):110. doi:10.1001/jama.1957.02980190112037

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This monograph presents a wealth of information on the potent analgesic drugs in a single volume. In view of the mass of literature on morphine and the morphine-like drugs, the task of preparing a comprehensive treatise on this subject was formidable. The authors have accomplished this objective in a capable manner. While not intended to be a complete review of the literature, this book does provide extensive information on the pharmacology of most of the known papaveraceous alkaloids and related synthetic substances. Morphine, the oldest, most widely used, and the most studied of all the alkaloids of opium, is discussed in the greatest detail. In addition to its pharmacology and toxicology, the chemistry, absorption, fate, and metabolism of morphine have received considerable attention as well as many aspects of the addiction phenomenon. Its therapeutic uses are briefly mentioned. The other natural and semisynthetic alkaloids, including those bases found in species

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