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July 21, 1956


JAMA. 1956;161(12):1153-1157. doi:10.1001/jama.1956.62970120001010

A form of diffuse pulmonary calcification called microlithiasis alveolaris pulmonum by Puhr,1 in 1933, has been reported sporadically only in European countries until recently, when two reports from the United States appeared simultaneously.2 The essential feature of this disease is a striking radiological appearance resembling miliary tuberculosis, caused by innumerable intra-alveolar concrements throughout the lung; in contrast to the degree of radiological and pathological changes, there are relatively few clinical symptoms until the late stages of the disease. Because of the increasing use of survey roentgenograms involving larger segments of the population, it is quite likely that this condition may be seen more frequently in the future. An awareness of its existence may lead to earlier recognition and avoidance of prolonged hospitalization. Since the pathology of our case has been described in detail elsewhere,2b the objective of this paper is to present clinical aspects of the disease

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