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September 21, 1957


JAMA. 1957;165(3):254-255. doi:10.1001/jama.1957.02980210050012

OR centuries skin eruptions in the diaper region have plagued infants and those responsible for their care. Kaessler1 states that few infants escape this condition entirely, and Benson and co-workers2 believe that in recent years the incidence of persistent diaper rash has increased. The term is somewhat of a misnomer, because in most cases the diaper itself is not the cause of the rash; but it is a convenient term for a group of unrelated conditions and is not likely to be abandoned. The commonest cause is the breaking down of urea with the resulting formation of ammonia. Bacterium ammoniagenes is the organism most commonly responsible for this. Other rashes in this region that may occur independently concomitantly are miliaria rubra or prickly heat, thrush, excoriation associated with diarrhea, intertrigo, seborrheic dermatitis, and allergy.3 A severe rash may be complicated by secondary infection and ulceration. Diaper rash