Statistically significant associations exist between the ABO blood groups and gastric cancer, peptic ulcer, and pernicious anemia. A study of the blood-type frequencies of Negro patients with gastric carcinoma and peptic ulcer showed an apparently higher incidence of gastric cancer in those with blood type A, and of peptic ulcer in those with blood type O. Only continuation and expansion of similar investigations, as well as other research, can adequately test the various hypotheses suggested by these blood group-disease associations.
Buckwalter JA, Turner JH, Raterman L, Tidrick RT, Knowler LA. ETHNOLOGIC ASPECTS OF THE ABO BLOOD GROUPS DISEASE ASSOCIATIONS. JAMA. 1957;165(4):327–329. doi:10.1001/jama.1957.02980220011003
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