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Article
October 12, 1957

RUBELLA AND PREGNANCY

JAMA. 1957;165(6):688. doi:10.1001/jama.1957.02980240046014
Abstract

OR AT LEAST 15 years it has been known that if rubella was contracted early in pregnancy serious harm to the developing embryo might result.1 Congenital malformations once thought to occur entirely by chance have more and more come to be recognized as a result of some maternal infection passed to the fetus through the placenta. Now, as pointed out by Greenberg and co-workers (this issue, page 675), many pregnant women and even some physicians believe that if rubella occurs in early pregnancy stillbirth or congenital malformation of the infant is inevitable. This impression is due primarily to two fallacies. Ingalls1 pointed out that early studies were retrospective, starting with malformed infants and getting a history of the diseases the mother had in pregnancy. Such studies take no account of illnesses occurring during pregnancy in women who delivered normal babies. It now appears that many women have normal

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