In an attempt to study the effect of zoxazolamine (Flexin) on children with cerebral palsy, we deemed a purely objective method of evaluation to be most advisable. Ninety-five children were selected at random, of whom 68 were spastics and 27 were athetoids. The diagnosis had been made by one or both of us. The youngest child was 2 years and 1 month of age and the oldest was 17 years. There was one adult, 28 years of age. The mean age was 8 years and 1 month (table 1).
There was a random distribution between the experimental and control groups with respect to intelligence levels, bracing, seizures, and whether the child was on therapy at the time of evaluation. Since these factors were randomly distributed, they were not considered to be of significance in the comparison of the experimental and control groups. If the child was on therapy, no effort
Watkins M, Hale MH. CLINICAL EVALUATION OF ZOXAZOLAMINE (FLEXIN) IN CHILDREN WITH CEREBRAL PALSY. JAMA. 1957;165(7):830–833. doi:10.1001/jama.1957.72980250005014c
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