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October 26, 1957


JAMA. 1957;165(8):949-951. doi:10.1001/jama.1957.72980260004007b

During the past few years the value of hypothermia in affording protection to vital tissues during circulatory occlusion has been cited in numerous articles. It is becoming a recognized procedure for certain cardiovascular and neurosurgical operations. The two principal complications subsequent to clamping the thoracic aorta are rapid dilatation and failure of left ventricular action and permanent damage to the spinal cord or kidneys due to ischemia.1 Cooling animals to 26 to 30 C (78 to 86 F) has prevented this heart failure and lesions of the extremities.2 The following case report is presented to show that, although moderate hypothermia (reduction of temperature to 31 C [88 F]) did not prevent cardiac failure secondary to a clamp being placed on the thoracic aorta for 50 minutes, it did afford complete protection of the kidneys and spinal cord during this period of total circulatory occlusion and the following hour

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