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November 2, 1957


JAMA. 1957;165(9):1178. doi:10.1001/jama.1957.02980270088023

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To the Editor:—  On Sept. 21, 1935, in The Journal (105:932-934), we reported a case diagnosed then as giant follicular malignant hyperplasia of the lymph follicles of the spleen, now better designated as follicular lymphoblastoma involving spleen. In this case the disease as first observed was confined to the spleen and several adjacent lymph nodes in the gastrosplenic omentum. There was no appreciable general lymph node involvement. A splenectomy was performed. The patient remained under our care until her death April 28, 1954, 27 years after the disease was recognized and diagnosed. As far as we know, this is the longest period of survival in this particular type of lymphoblastoma, the giant follicular type. Usually death occurs within 10 years. Unfortunately an autopsy was not obtained, but the clinical and laboratory findings suggested that the death was due to lymphosarcoma which had ultimately developed from the follicular lymphoblastoma. From

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