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November 2, 1957

An Atlas of Muscle Pathology in Neuromuscular Diseases

JAMA. 1957;165(9):1214. doi:10.1001/jama.1957.02980270124028

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This book consists essentially of an excellent collection of photographs, about half of them in color, showing the abnormalities of the microstructure of voluntary muscle in various neuromuscular diseases. The plates are arranged in 10 sets, the first set illustrating loss of cross striation, cloudy and granular changes, floccular changes, and phagocytosis. The other nine sets illustrate changes in muscle nuclei, changes in fiber size, basophilic fibers with vesicular nuclei and prominent nucleoli, ringed fibers, sarcoplasmic masses, changes in interstitial tissues (corlagen and fat), leukocytic infiltrations, changes in muscle spindles and peripheral muscular nerves, and pattern of lesion. By excluding trauma, infections, and tumors from consideration, the authors were able to exhibit in greater detail and to better advantage the amazing variety of ways in which the elaborate structure of the sarcostyle can be disorganized by more strictly neuromuscular disease. Examples of such disorganization are the occurrence of aberrant nuclei

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