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July 28, 1956


JAMA. 1956;161(13):1275. doi:10.1001/jama.1956.02970130063023

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To the Editor:—  One particular in the otherwise excellent editorial entitled "Serotonin" in The Journal, June 2, 1956, page 460, could readily be misconstrued. The second paragraph notes the interesting studies of Erspamer and his colleagues on the substance they called enteramine and considered to be a phenolic amine until, by adopting paper chromatography, they were able to identify this substance with serotonin (5-hydroxytryptamine) not "in 1952," but in 1951 (Erspamer and Boretti: Arch. internat. pharmacodyn.88:296, 1951). Chronology suffers more severely in the next sentence, for the editorial goes on to state that "Meanwhile, Page and his associates had succeeded in isolating and identifying as 5-hydroxytryptamine a substance from blood serum long known to possess vasoconstrictive properties... previously... known by a variety of names, including serotonin and vasotonin." In my dictionary (Webster's New World) meanwhile has the meanings "in or during the intervening time" or "at the same

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