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November 16, 1957

Systemic Arterial Embolism: Pathogenesis and Prophylaxis

JAMA. 1957;165(11):1512. doi:10.1001/jama.1957.02980290152028

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This monograph reviews in an orderly fashion the problem of embolism of peripheral arteries. The basis for the review is an extensive bibliography citing almost 300 references. The statistics bearing directly on the problem of embolism are all derived from these articles. The book also deals with the various forms of heart disease which are described as being the major causes of arterial embolism in the chapter Differential Diagnosis of Heart Disease. The fact that the condition of a high proportion of patients with rheumatic heart disease goes without accurate diagnosis during life is pointed out. Major arterial embolism may be the first sign of mitral stenosis, and careful search in such patients should disclose the underlying cause of the arterial accident. Parts of this chapter appear to be somewhat beside the point. Other sections dealing with rheumatic fever and its relation to prophylactic anticoagulant therapy are excellent. A large

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