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December 28, 1957


JAMA. 1957;165(17):2219. doi:10.1001/jama.1957.02980350077023

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To the Editor:—  In the Sept. 28, 1957, issue of The Journal, page 392, we described a routine diaper test for the early detection of phenylketonuria which is being evaluated in well-baby clinics of southern California. In this study the wet diaper of each infant is tested with a drop of 10% ferric chloride at each visit to the clinic during the first year of life. Hearing about our project, Dr. M. D. Armstrong of the University of Utah kindly informed us of a somewhat similar detection program in England. This program is being initiated this year by Dr. L. I. Woolf of the Hospital for Sick Children, Great Ormond Street, London. We have recently corresponded with Dr. Woolf and we believe Journal readers might be interested in hearing about the approach to this problem in another country. An illustrated card describing the test and its purpose is made available

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