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August 11, 1956


JAMA. 1956;161(15):1484-1485. doi:10.1001/jama.1956.02970150052012

The physician who devotes an appreciable amount of his time and effort to the treatment of the lymphomas and leukemias is often accosted with the comment from his medical colleagues that such must be "a discouraging business." Actually, in the treatment of such patients one does at times experience a feeling of despair, but not one of complete hopelessness or frustration, because much can be done for these individuals and great gratification can accrue from this, especially since the addition of the newer available therapeutic agents. Of particular interest is the patient with Hodgkin's disease ( lymphogranulomatosis), for several reasons. The disease is protean in its manifestations and often offers a real challenge diagnostically. In varying degrees it resembles both tumor and infection in its course, which is frequently bizarre in individual patients. Actually, it is conceivable that this may be a tumor with a virus or infectious etiology. The prognosis

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