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August 25, 1956

Techniques in Blood Grouping

JAMA. 1956;161(17):1715-1716. doi:10.1001/jama.1956.02970170111029

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With the development of new methods of detecting isoantibodies that are capable of causing hemolytic transfusion reactions or of causing the development of erythroblastosis in a newborn baby, there is need for an up-to-date manual that presents the best techniques in readily accessible form to the busy blood bank technician. This book is a mine of such information, clearly and conveniently presented. Its usefulness is impaired, however, by its reiteration of the misinformation and misconceptions that have marred blood group literature in recent years. On page 6, there is a good discussion of the difference between an agglutinogen and a blood factor, but this seems to be forgotten in the remainder of the book, since the authors adhere to the simple but incorrect concept of a one-to-one correspondence between antigen and antibody. The C-D-E notations for the Rh-Hr types and their attendant paradoxes are the natural sequel of the fallacious

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