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Article
January 18, 1958

THE SOLITARY CIRCUMSCRIBED PULMONARY NODULE: STUDY OF SEVEN HUNDRED FIVE CASES ENCOUNTERED ROENTGENOLOGICALLY IN A PERIOD OF THREE AND ONE-HALF YEARS

Author Affiliations

Rochester, Minn.

From the Section of Roentgenology, Mayo Clinic and Mayo Foundation (Dr. Good). Dr. Wilson is a Fellow in Radiology, Mayo Foundation. The Mayo Foundation is a part of the Graduate School of the University of Minnesota.

JAMA. 1958;166(3):210-215. doi:10.1001/jama.1958.02990030008003
Abstract

The histories of 705 patients with solitary circumscribed pulmonary masses have been analyzed. In 294 instances the masses appeared roentgenographically to be calcified, and in their subsequent course none of these gave any evidence of malignancy. In 103 instances the masses accompanied a known extrapulmonary malignant neoplasm, and at least 86 of these proved to be metastatic. In 37 instances nodules were known to have been stable as to size for two years or more, but evidence as to their nature was incomplete. It is advisable to keep both calcified and stable nodules under observation, but the possibility that a malignant lesion is present is greater in the stable, noncalcified than in the calcified masses.

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