Factors that might predispose to myocardial infarction were studied in 209 persons who developed that condition during a one-year period. The most striking factor was sex, in that the incidence for women was only 0.2 case per 1,000 while that for men was 2.9 cases per 1,000. The probability of recovery was slightly greater in patients not classed as hypertensive, but the difference was within the range of sampling error. The risk of myocardial infarction in patients with both hypertension and overweight was 3.5 times greater than that in patients with neither handicap, but there was no evidence that the immediate prognosis, after an attack had occurred, was affected by overweight, hypertension, or a history of tachycardia.
Pell S, D'Alonzo CA. MYOCARDIAL INFARCTION IN A ONE-YEAR INDUSTRIAL STUDY. JAMA. 1958;166(4):332–337. doi:10.1001/jama.1958.02990040018004
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