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Article
February 8, 1958

ANTIBACTERIAL, VASOPRESSOR, AND STEROID ADJUVANTS IN UROLOGIC SURGERY

Author Affiliations

Philadelphia

From the Harrison Department of Surgical Research, School of Medicine, and the Department of Surgery, Division of Urology, Hospital of the University of Pennsylvania.

JAMA. 1958;166(6):616-618. doi:10.1001/jama.1958.02990060054012
Abstract

In the lower urinary tract, where instrumental examination and treatment involves trauma to infected areas, there is abundant evidence that invasion of micro-organisms does occur. There is general agreement that overt infection should be treated prior to surgery, preferably by specific drugs as determined by sensitivity studies made upon the organism or organisms cultured by reliable techniques. The armamentarium of the urologic surgeon includes antibacterial agents, vasopressor substances, and the adrenal cortical steroids. Vasopressor agents are commonly employed for the maintenance of blood pressure when this is lowered by factors other than blood loss. Hydrocortisone given intravenously has proved to be of inestimable value in the management of the shock-like state occasionally seen after or accompanying bacteremia.

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