This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
The development of our knowledge of the biological behavior of brain tumors, as deduced from their pathological appearances, was one of the chief contributions from the clinic of the late Harvey Cushing. The gliomas were studied by Percival Bailey and glioma cells, classified according to cell types, were compared with the cells of normal brain tissue. To this basic study Bailey and Cushing added a survey of the clinical course and prognosis of brain tumors, thus bringing order out of the previous chaos. The different forms and types, moreover, were correlated with a particular survival period, and note was made of tumors showing a preference for certain age groups and various sites of origin. The "American classification" of Bailey and Cushing (1926) was accepted throughout the world and, with a few modifications, is the basis for the current concept of brain tumors. This classification has been somewhat simplified in recent
Brain Tumors: Their Biology and Pathology. JAMA. 1958;166(12):1534. doi:10.1001/jama.1958.02990120126029
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: