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September 27, 1958

Advances in Cancer Research. Volume V

JAMA. 1958;168(4):470-471. doi:10.1001/jama.1958.03000040106023

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This book should be of interest to experimentalists in several disciplines but will be of little interest to the average clinician except in its discussions of primary cancer of the liver (by Berman, of South Africa) and of tumor-host relations (by Begg, of the University of Western Ontario). Other topics discussed are protein synthesis and growth processes, the newer concept of cancer toxin, chemically induced tumors of fowls, anemia in cancer, specific tumor antigens, and the chemistry and carcinogenicity of 2-fluorenamine and related compounds. The international flavor of the volume is indicated by contributions from Russia, England, Japan, Scotland, and the United States. Berman concludes that environmental factors, both cirrhotogenic and carcinogenic, are probably responsible for hepatic neoplasia occurring in a favorably prepared "soil" largely determined on a nutritional basis. Price and Greenfield (of the National Cancer Institute, U. S. Public Health Service) emphasize the inadequacy of understanding of the

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