[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 18.204.55.168. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
December 20, 1958

CURRENT STATUS OF THE TREATMENT OF ADRENAL DISORDERS

Author Affiliations

Boston

From the departments of medicine, Harvard Medical School and the Peter Bent Brigham Hospital (Drs. Thorn, Renold, and Nelson) and investigator, Howard Hughes Medical Institute (Dr. Nelson).

JAMA. 1958;168(16):2130-2137. doi:10.1001/jama.1958.63000160007011

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

The availability of precise diagnostic techniques and the synthesis of several important adrenal cortical steroids provide the practicing physician with an unusual opportunity for establishing a correct diagnosis and initiating appropriate therapy in patients with abnormalities of adrenal cortical function. The ever-widening horizon of the nonspecific use of adrenal steroid therapy and the exploration of the beneficial effect of hypophysectomy and adrenalectomy have increased greatly the numbers of patients with evidence of altered adrenal cortical function. The development of accurate and clinically applicable measurements of catechol amine levels in blood and urine has enhanced the accuracy with which pheochromocytoma may be detected and has provided a new and important screening technique which should be applied to all patients with hypertension of undetermined origin.

Hormone Preparations  The structural formulas of the adrenal steroid compounds are represented in figure 1.

Corticotropin.—  Corticotropin ( Acth, Lyophilized Acthar, Corticotropin, Lyophilized Corticotropin), also known as

First Page Preview View Large
First page PDF preview
First page PDF preview
×