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January 3, 1959


Author Affiliations

230 N. Broad St., Philadelphia 2.

JAMA. 1959;169(1):68-69. doi:10.1001/jama.1959.03000180070021

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To the Editor:—  The appearance of a new laboratory aid in the differential diagnosis of the collagen diseases usually produces some excitement in the medical profession. This is especially true in the study of disseminated lupus erythematosus, because the only reliable laboratory aid to the diagnosis has been the demonstration of L. E. cells, a finding which may be inconstant and require some skill in performance and interpretation. For this reason, the description of a precipitation test by Jones and Thompson in The Journal (166:1424-1428 [March 22] 1958) proved to be of real interest to physicians. In many hospitals and clinical laboratories it was offered immediately as a diagnostic test. To others, this test represented an opportunity for further study, if only to determine the nature of the precipitate formed and to shed light on the defect responsible for its production.We have had the opportunity to study this

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